Companies Hub: Human Simulation Industry Leaders

ORGAN-ON-CHIP LEADERS

Platform Leader

Emulate

FDA ISTAND-qualified Liver-Chip. 87% sensitivity for DILI prediction. Wyss Institute spinout.

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Multi-Organ

CN Bio

PhysioMimix multi-organ MPS. Liver, gut, and multi-organ platforms for ADME-Tox.

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Body-on-Chip

Hesperos

Human-on-a-Chip platform. Multi-organ pumpless systems for systemic drug response.

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HUMIMIC

TissUse

HUMIMIC multi-organ chips. German engineering for systemic pharmacology.

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OrganoPlate

Mimetas

OrganoPlate 3-lane microfluidic platform. High-throughput organ-on-chip.

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Neural

AxoSim

Nerve-on-chip technology. Peripheral nerve and CNS models.

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ORGANOID SPECIALISTS

Biobank

HUB Organoids

Netherlands biobank. Acquired by Merck Dec 2024. Hans Clevers founded.

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Tumor Models

Crown Bioscience

HuTumorX organoid platform. Patient-derived tumor models.

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3D InSight

InSphero

3D InSight liver and islet microtissues. Scaffold-free spheroids.

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AI & DIGITAL TWIN

AI Platform

Recursion

$1B+ AI drug discovery. Acquired Cyclica, Valence. Nvidia partnership.

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Generative AI

Insilico Medicine

Chemistry42, Biology42. AI-designed drugs in clinical trials.

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Bio-AI

Quris AI

Patient-on-chip + AI integration. Predictive toxicology platform.

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