L'OR→ALLyon, FranceOECD Validated
Reconstructed Skin Pioneer

EpiSkin

L'Or→al's SkinEthic Reconstructed Tissue Models

← Back to Companies

COMPANY OVERVIEW

EpiSkin SAS, a subsidiary of L'Or→al headquartered in Lyon, France, is a pioneer in reconstructed human tissue models. The company developed OECD-validated skin and cornea models for safety testing, supporting L'Or→al's commitment to eliminate animal testing while also commercializing products to the broader cosmetics and pharmaceutical industries.

PRODUCT PORTFOLIO

  • EpiSkin: Reconstructed human epidermis for skin irritation/corrosion testing
  • SkinEthic RHE: Reconstructed human epidermis models (OECD TG 439)
  • SkinEthic HCE: Human cornea-like epithelium for eye irritation (OECD TG 492)
  • SkinEthic RhE Pigmented: Melanocyte-containing models for skin lightening studies
  • SkinEthic HGE: Human gingival epithelium for oral care product testing

REGULATORY VALIDATION

  • OECD TG 431: EpiSkin validated for skin corrosion
  • OECD TG 439: EpiSkin and SkinEthic validated for skin irritation
  • OECD TG 492: SkinEthic HCE validated for eye irritation
  • EU Reference Methods: Listed in EU cosmetics regulation annexes

L'OR→AL INTEGRATION

EpiSkin enables L'Or→al to maintain its leadership in cruelty-free cosmetics development, having screened over 4,000 ingredients and 600 products annually without animal testing. The models also support L'Or→al's personalized beauty initiatives through testing on diverse skin types and phototypes.

→ Companies Hub