EVALUATION FRAMEWORK
Vendor selection should match your specific application needs. Consider scientific fit (does the model address your question→), operational requirements (throughput, expertise needed), regulatory pathway (validation status), and commercial terms (pricing model, IP rights). Pilot studies before commitment are essential.
KEY SELECTION CRITERIA
- Scientific Validation: Published data, pharma partnerships, regulatory submissions
- Model Complexity: Single organ vs. multi-organ, static vs. perfused, cell sources
- Throughput: Low-throughput mechanistic vs. high-throughput screening
- Technical Support: Training, protocol optimization, troubleshooting
- Cost Structure: Consumables, equipment, service fees, per-sample pricing
SERVICE MODELS
- Product Purchase: Buy platforms/consumables, run studies in-house (Emulate, CN Bio)
- CRO Services: Outsource studies to vendor laboratories (Crown Bioscience, InSphero)
- Hybrid: Vendor installs system on-site with ongoing support
- Biobank Access: License organoid lines from established collections (HUB)
- Co-Development: Joint development of custom models for specific applications
DUE DILIGENCE
Request reference customers in similar applications. Review published validation data critically. Understand IP implications→some platforms restrict data publication or require co-authorship. Negotiate data ownership upfront. Evaluate vendor financial stability for long-term partnerships. Site visits assess operational quality.